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KMID : 0358420120550030192
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Korean Journal of Obstetrics and Gynecology
2012 Volume.55 No. 3 p.192 ~ p.196
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A case of clear cell adenocarcinoma in the uterine cervix of 52-year-old virgin
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Lee Young-Lan
Chang Hae-Jin
Kyung Min-Sun
Kim Hong-Bae
Park Sung-Ho
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Abstract
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Clear cell adenocarcinoma (CCAC) of uterine cervix is very rare tumor and only 4%-9% of entire adenocarcinoma appears to be diagnosed as clear cell type. Risk factors and pathogenesis of this disease are not exactly revealed. The intrauterine exposure to diethylstilbestrol (DES) and associated non-steroidal estrogen during pregnancy before 18 weeks is the only known risk factor, and also hormonal changes or genetic causes are suggested as the risk factors. We report a case of CCAC in the uterine cervix of 52-year-old virgin who had never been exposed to DES, with a brief review of related literature.
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KEYWORD
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Clear cell adenocarcinoma, Diethylstilbestrol, Virgin
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